Vaginal ozone therapy is a supportive, integrative treatment used to help optimize vaginal health and local immune function. This therapy utilizes medical-grade ozone (O₂/O₃), a highly activated form of oxygen, applied locally to the vaginal area under medical supervision. Vaginal ozone therapy has been studied for its antimicrobial properties and its potential role in supporting the body’s natural defenses.
What Is Vaginal Ozone Therapy?
Ozone therapy is a form of oxygen-based therapy that has been used in medical settings for decades. When applied vaginally, ozone may be delivered in controlled, medical-grade doses through gentle insufflation or other physician-directed methods. Treatments are typically brief and performed in a clinical environment.
Ozone is known for its bactericidal, antiviral, and antifungal properties, while also helping to preserve the balance of normal vaginal flora. Rather than masking symptoms, vaginal ozone therapy is designed to support the body’s local immune response and promote a healthier vaginal environment.
Conditions That May Benefit from Vaginal Ozone Therapy
Vaginal ozone therapy may be considered as part of a comprehensive, integrative care plan for individuals experiencing:
- Recurrent yeast infections
- Bacterial vaginosis (BV)
- Chronic or recurrent vaginal infections
- Vaginal irritation, burning, or abnormal discharge
- Cervicitis (inflammation of the cervix)
- Persistent human papillomavirus (HPV) infections under medical supervision
Vaginal ozone therapy is not a replacement for routine gynecologic care, Pap smears, or standard medical treatments, but may be used as a complementary option when appropriate.
How Vaginal Ozone Therapy Works
Ozone therapy works through several supportive mechanisms:
- Helps reduce pathogenic bacteria, viruses, and fungi
- Supports local immune modulation within vaginal tissues
- Enhances oxygen utilization at the cellular level
- Promotes tissue balance without significantly disrupting beneficial vaginal flora
By improving the local environment, ozone therapy may help the body respond more effectively to chronic or recurrent vaginal concerns.
A Comprehensive Approach to Recurrent Vaginal Infections
Vaginal ozone therapy is most effective when used as part of an individualized, whole-person treatment plan. Additional supportive steps may include:
- Baseline Testing
Advanced vaginal and urinary PCR testing may be used to evaluate the vaginal microbiome, identifying bacterial or fungal organisms that are not detected with routine testing. Blood work may also be recommended to assess immune and nutritional status. - Immune System Support
Optimizing immune health through balanced nutrition, adequate sleep, stress management, and targeted supplementation is an essential foundation of care. - Hormonal Balance
Hormonal imbalances may contribute to recurrent vaginal infections. When appropriate, hormone evaluation and management may be considered. - Nutritional & Herbal Support
Certain supplements and botanicals—such as probiotics, vitamin C, zinc, vitamin A, L-lysine, garlic, or berberine—may be recommended based on individual needs and under professional guidance.
Clinical Evidence & Research Reference
Vaginal ozone therapy has been evaluated in clinical research settings. A published study in the Revista Española de Ozonoterapia (Schwartz, A., 2017) examined intravaginal ozone therapy in women with persistent human papillomavirus (HPV) infections that had not resolved spontaneously. The study observed improved outcomes, particularly when ozone therapy was combined with integrative medical support, suggesting a potential synergistic benefit.
While ongoing research is needed, existing evidence indicates that intravaginal ozone therapy may be a safe and well-tolerated adjunctive approach when used appropriately and under medical supervision.
What to Expect During Treatment
- Treatments are performed in-office by trained medical professionals
- Sessions are generally brief and well-tolerated
- Treatment plans are customized based on symptoms, testing, and medical history
- The number of sessions varies depending on individual needs and response
Schedule a Consultation
If you are experiencing recurrent vaginal infections or are interested in integrative approaches to vaginal health, a personalized consultation can help determine whether vaginal ozone therapy may be appropriate for you.
📞 Call to schedule:
Rockford Office: 815-398-7246
Chicago Office: 312-808-1200
Vaginal ozone therapy is offered as part of an integrative medical approach and is not intended to diagnose, treat, cure, or prevent disease. Individual results may vary. Please consult with a qualified healthcare provider to determine the best course of care for your health needs.







